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Translational Cardiology Research Laboratory

The Translational Research Laboratories conducts a number of important bench-bedside themes of research in close collaboration with other groups within the Kolling Institute and Royal North Shore Hospital.

  • Research from the laboratory has defined a key role for the early immediate transcriptional factor Egr-1 in the pathogenesis of ischaemia reperfusion injury in a heart attack model. They have also discovered its role in mediating the protective effects of ischaemic preconditioning. The laboratory team continue to unravel the signaling pathways involved in these processes.
  • Work is being undertaken using advanced percutaneous coronary techniques, intravascular imaging and physiology technologies combined with molecular to understand and improve outcomes in a number of complex settings including patients with stable and unstable coronary disease, chronic total occlusions, failing saphenous grafts, atrial fibrillation and spontaneous coronary dissection. This work is being conducted locally and in collaboration with other sites nationally and internationally.
  • Percutaneous valve therapies. The North Shore Hospital Campus is involved in research into percutaneous aortic and mitral valve therapies. These studies extend from experimental models through to clinical trials.

Translational Cardiology Director - Associate Professor Ravinay Bhindi

Theme

Combatting Chronic Disease

Networks

Cardiothoracic & Vascular Health

 


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