The Raymond Purves Bone and Joint Research Laboratories (RPRL) is the basic science research arm of the Department of Orthopaedics. The physical co-location and close affiliation between the RPRL scientists and orthopaedic surgeons at Royal North Shore Hospital means our research has a real translational focus - answering clinically important questions to improve the health of patients. The RPRL leads Australia in research into the cell and molecular mechanisms underlying some of the key musculoskeletal (bone and joint) diseases affecting our population: osteoarthritis, tendon injury and repair, and intervertebral disc degeneration. Only through a better understanding of the pathways that drive the initiation and progression of these disabling conditions will disease modifying therapies be developed.
Raymond Purves Bone & Joint Research Laboratory Head - Professor Christopher Little